Source: CVC IN SAN DIEGO PROCEEDINGS
November 1, 2010
By:
Lara K. Maxwell, DVM, PhD, DACVCP
Identification and correction of the underlying causes of arrhythmias are key to their long-term, successful management. For instance, in a cat with atrial standstill as a result of hyperkalemia from urethral obstruction, the arrhythmia is best addressed by correction of the underlying problem, hyperkalemia, as primary antiarrhythmic therapy is generally unsuccessful when such electrolyte abnormalities are present.
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Source: CVC IN SAN DIEGO PROCEEDINGS
November 1, 2010
By:
Dawn M. Boothe, DVM, PhD, DACVIM, DACVCP
The ability of organisms to develop resistance to an antimicrobial varies with the species and strain. Many organisms remain predictably susceptible to selected drugs (eg, Brucella, Chlamydia); whereas others are becoming problematic (Pasteurella multocida).
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Source: CVC IN SAN DIEGO PROCEEDINGS
November 1, 2010
By:
Lara K. Maxwell, DVM, PhD, DACVCP
As their name implies, nonsteroidal aniti-inflammatory drugs (NSAIDs) are used in the treatment of inflammatory conditions, which are characterized by redness, swelling, heat, pain, and loss of function. Although the inflammatory response can be viewed as essentially protective and beneficial to the body, excessive inflammation in the face of progressive disease can promote the cycle of increasing damage and inflammation.
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Source: CVC IN SAN DIEGO PROCEEDINGS
November 1, 2010
By:
Dawn M. Boothe, DVM, PhD, DACVIM, DACVCP
Successful control of seizures with anticonvulsant drugs reflects a balance in achieving seizure control while minimizing undesirable drug side effects. Variability in the disposition of anticonvulsants and interactions among them and other drugs are important confounders of successful therapy.
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Source: CVC IN SAN DIEGO PROCEEDINGS
November 1, 2010
By:
Dawn M. Boothe, DVM, PhD, DACVIM, DACVCP
Individualized drug therapy increasingly is being recognized as an important aspect of health care for both human and veterinary medicine. However, the number of animal drugs approved by the Food and Drug Administration (FDA) is sparse in comparison to those for human patients.
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Source: CVC IN SAN DIEGO PROCEEDINGS
November 1, 2010
By:
Dawn M. Boothe, DVM, PhD, DACVIM, DACVCP
Today's drug package insert (DPI) can be a powerful ally in the selection and judicious use of a drug. The information that it provides might be categorized as either Product Description, Product Efficacy or Product Safety with some overlap among the categories.
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Source: CVC IN SAN DIEGO PROCEEDINGS
November 1, 2010
By:
Dawn M. Boothe, DVM, PhD, DACVIM, DACVCP
Dosing regimens for antimicrobials exemplify the integration of pharmacokinetics (what the body does to the drug) and pharmacodynamics (what the drug does to the body). For antimicrobial therapy, the "body" is the microbe.
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Source: CVC IN SAN DIEGO PROCEEDINGS
November 1, 2010
By:
Lara K. Maxwell, DVM, PhD, DACVCP
In the therapy of neoplastic infections with cytotoxic drugs, there is little basis for the selective killing of the abnormal cells as opposed to the healthy cells in the body. There are only a few known differences in receptors and metabolism that are suitable drug targets at the present time.
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Source: CVC IN SAN DIEGO PROCEEDINGS
November 1, 2010
By:
Lara K. Maxwell, DVM, PhD, DACVCP
Small animal practitioners are well aware that "cats are not small dogs". However, are small dogs just miniaturized versions of their larger brothers and sisters? What about the effect of breed on therapeutics? The incredible diversity of dog breeds presents veterinarians with problems and opportunities inherent to the medical care for such a highly variable species.
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