Image Quiz: Dermatology—A bulldog with erythematous plaques

Jul 19, 2010
By staff

Lymphoma is correct!

Cytology of cutaneous lymphoma shows neoplastic lymphocytes ranging in size from small to large, with round, indented, or convoluted nuclei. Basophilic cytoplasm is scant to moderate. Uniformity of the lymphoid population without significant inflammation or plasma cell infiltration is suggestive of cutaneous lymphoma, but biopsy is required for definitive diagnosis. Biopsy will help differentiate between epitheliotropic and nonepitheliotropic lymphoma, which can affect the chemotherapy choices and prognosis.