Immunology | Veterinary Medicine

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Immunology

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CVC IN KANSAS CITY PROCEEDINGS: Aug 01, 2011
Feline herpesvirus (FHV) is a common pathogen of domestic cats. The virus is a ds DNA virus with a lipid envelope. The virus primarily targets epithelia of the upper respiratory tract and conjunctiva, and only rarely spreads beyond these regions to cause disease.
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CVC IN KANSAS CITY PROCEEDINGS: Aug 01, 2011
Why??? One of two goals: Enhancing the immune response (e.g. infection, cancer); or 2) suppressing the immune response (e.g. autoimmune disease). Results are often broad in scope, when usually we want a focused effect; for example, enhancing certain components of the immune response, like CMI in FIP, or suppressing only certain components of the immune response, like B lymphocytes that recognize an allergen, and produce IgE.
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CVC IN KANSAS CITY PROCEEDINGS: Aug 01, 2011
There are a plethora of commercially available vaccines available for use in cattle, the majority of which target viral and bacterial pathogens of the respiratory and enteric tracts.
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CVC IN KANSAS CITY PROCEEDINGS: Aug 01, 2011
Molecular diagnostics have quickly become a mainstay in veterinary medicine, particularly in the area of infectious diseases. With the rapid advancement of technology, it is difficult to keep up with what is available as well as to understand what the results mean.
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CVC IN KANSAS CITY PROCEEDINGS: Aug 01, 2011
Immunology plays a huge role in diagnostics for infectious diseases. In addition, various assays are able to assess the immune system itself in an animal.
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CVC IN KANSAS CITY PROCEEDINGS: Aug 01, 2011
The immune system has two arms of defense, nonspecific and specific. As with the immune system in total, there are many elements of the nonspecific arm of the immune response. These have in common their lack of strict recognition of foreign material and absence of memory.
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CVC IN KANSAS CITY PROCEEDINGS: Aug 01, 2011
An outbreak of respiratory disease occurred in a kennel of racing greyhounds in 2004. While some dogs exhibited mild disease with fever and cough, some experienced peracute death with pulmonary hemorrhage (case fatality 36%). Virologic analysis revealed an influenza virus that was later found to be closely related to equine influenza virus subtype H3N8, sharing >96% genetic sequence identity.
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CVC IN KANSAS CITY PROCEEDINGS: Aug 01, 2011
Immunoprophylaxis is the enhancement of a specific immune response to the specific pathogen. Humoral and cell-mediated immune response are critical to effective immunity. This response is induced by microbes, their components or by-products. The majority of vaccines prevent infectious disease, but not infection.
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CVC IN KANSAS CITY PROCEEDINGS: Aug 01, 2011
The primary role of the immune system is to protect against infectious disease. The mechanisms employed vary in efficiency for intra- vs extracellular pathogens. Nonspecific immunologic resistance involves interferon – stimulates production of proteins with antiviral activity.
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CVC IN KANSAS CITY PROCEEDINGS: Aug 01, 2011
FIP – nothing's ever simple....It is a multifactoral disease involving virus factors, host factors, and environmental factors. The virus of FIP is feline coronavirus (FCoV) – interestingly, it is required but not sufficient for FIP. Coronaviruses have a large RNA genome.
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VETERINARY MEDICINE: Jun 01, 2011
Outbreaks of equine viral arteritis can be devastating to the equine industry.
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DVM360 MAGAZINE: Jun 01, 2011
Ithaca, N.Y. — Veterinary immunologists at Cornell believe their work with Toxoplasma and development of Crohn's disease offers new insights into the prevention and treatment of a slew of autoimmune disorders.
May 01, 2011
Prednisone is almost always included in immunosuppressive protocols. The dose is approximately 2.2 mg/kg once daily for most cases; 1 mg/kg in less severe diseases.
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VETERINARY MEDICINE: Mar 01, 2011
A recent study examined the safety and efficacy of orally administered famciclovir in cats experimentally infected with a pure strain of FHV-1.
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VETERINARY MEDICINE: Jan 06, 2011
The history of canine influenza virus began with the identification of infections in racing greyhounds, directing research that defined canine influenza virus (CIV), a variant of equine influenza virus with a unique genetic signature capable of being transmitted from dog to dog.