If you are performing staging, remember that ultrasonography cannot differentiate metastatic disease from common aging changes in older dogs. For example, to differentiate nodular hyperplasia of the liver from nodular metastatic disease and avoid an erroneously poor prognosis, always perform fine-needle aspiration or biopsy of the liver.
Annette N. Smith, DVM, MS, DACVIM (oncology & small animal internal medicine)
Department of Clinical Sciences
College of Veterinary Medicine
Auburn, AL 36849