Chronic renal failure is common in geriatric cats and dogs, and deteriorating kidney function is compounded by a catabolic state responsible for many of the complications of this disease, such as anemia and weight loss.
Despite recent technological advances in dialysis and transplantation, conservative medical management remains the most practical and accessible approach to the treatment of chronic renal failure (CRF) for most cat owners and veterinarians.
Polycystic kidney disease was first described in adult male and female long-haired, Persian-type cats in the late 1960's. In 1996, the disorder was shown to be inherited as an autosomal dominant trait in a family of Persian cats. Both male and female cats were affected. In affected ? unaffected crosses, 42% of offspring were affected and 58% were unaffected. In affected ? affected crosses, 73% of progeny were affected and 27% were unaffected.
Chronic Kidney Disease (CKD) is common in geriatric cats but often appears stable for long periods of time. Several studies have evaluated prognostic markers in cats with CKD, but few have identified which ones precede disease progression. The aim of this study was to find a marker which would predict deterioration of renal function in cats newly diagnosed with CKD.
Less than 1% of the total body phosphorus is in the plasma with 1/3 of this as inorganic phosphate ions, most of which are unbound. Laboratory analysis of serum phosphorus measures all forms of H3PO4 (H3PO4, H2PO4, HPO4) referred to as inorganic phosphate. Serum phosphate levels are higher in serum than plasma due to the clotting process that releases phosphorus from cells and platelets.