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Image Quiz: A Lab with a penile mass
Vincristine is correct!
The location and gross appearance of this lesion are strongly suggestive of a transmissible venereal tumor. This impression is confirmed by the cytologic features, including round cells with discrete cell margins and a moderate amount of light-blue cytoplasm containing punctate vacuoles. Nuclei are round and often contain a single prominent nucleolus. Chemotherapy is the most effective treatment modality, and vincristine is one of the most effective agents, with a cure expected in 90% of patients treated with four to six once-weekly treatments.1 Surgery is effective for small, localized cutaneous nodules, but adequate excision is rarely possible when the tumor involves external genitalia. Radiation therapy may also be effective. Reference |
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