Current treatment options for dogs with appendicular osteosarcoma - Veterinary Medicine
Medicine Center
DVM Veterinary Medicine Featuring Information from:


Current treatment options for dogs with appendicular osteosarcoma
Your therapeutic choices for dogs with osteosarcoma in their limbs continue to expand. Deciding which option is best comes down to the site and extent of the tumor and the owner's preference.


28. Dick HM, Strauch RJ. Infection of massive bone allografts. Clin Orthop 1994;306:46-53.

29. Aronson J. Limb-lengthening, skeletal reconstruction, and bone transport with the Ilizarov method. J Bone Joint Surg Am 1997;79:1243-1258.

30. Dernell WS, Withrow SJ, Straw RC, et al. Clinical response to antibiotic impregnated polymethyl methacrylate bead implantation of dogs with severe infections after limb sparing and allograft replacement-18 cases (1994-1996). Vet Comp Orthop Traumatol 1998;11:94-99.

31. Thrall DE, Withrow SJ, Powers BE, et al. Radiotherapy prior to cortical allograft limb sparing in dogs with osteosarcoma: A dose response assay. Int J Radiat Oncol Biol Phys 1990;18:1351-1357.

32. Liptak JM, Dernell WS, Lascelles BDX, et al. Survival analysis of dogs with appendicular osteosarcoma treated with limb-sparing surgery and adjuvant carboplatin or carboplatin and doxorubicin, in Proceedings. 21st Annu Vet Cancer Soc Conf 2001;39.

33. Ilizarov GA. The tension-stress effect on the genesis and growth of tissues. In: The Transosseous osteosynthesis. Berlin, Germany: Springer-Verlag, 1992;137-255.

34. Aronson J. Cavitary osteomyelitis treated by fragmentary cortical bone transportation. Clin Orthop 1992;280:153-159.

35. Villa A. Isolated radial lengthening. In: Bianchi Maiocchi A, ed. Advances in Ilizarov apparatus assembly. Milan, Italy: Medicalplastic srl, 1985;90.

36. Welch RD, Lewis DD. Distraction osteogenesis. Vet Clin North Am Small Anim Pract 1999;29:1187-1205.

37. Cierny G 3rd, Zorn KE. Segmental tibial defects. Comparing conventional and Ilizarov methodologies. Clin Orthop 1994;301:118-123.

38. Cattaneo R, Catagni M, Johnson EE. The treatment of infected nonunions and segmental defects of the tibia by the methods of Ilizarov. Clin Orthop 1992;280:143-152.

39. Minematsu K, Tsuchiya H, Taki J, et al. Blood flow measurement during distraction osteogenesis. Clin Orthop 1998;347:229-235.

40. Berg J, Weinstein MJ, Schelling SH, et al. Treatment of dogs with osteosarcoma by administration of cisplatin after amputation or limb-sparing surgery: 22 cases (1987-1990). J Am Vet Med Assoc 1992;200:2005-2008.

41. Ehrhart N, Eurell JA, Tommasini M, et al. Effect of cisplatin on bone transport osteogenesis in dogs. Am J Vet Res 2002;63:703-711.

42. Withrow SJ, Thrall DE, Straw RC, et al. Intra-arterial cisplatin with or without radiation in limb-sparing for canine osteosarcoma. Cancer 1993;71:2484-2490.

43. Ramirez O 3rd, Dodge RK, Page RL, et al. Palliative radiotherapy of appendicular osteosarcoma in 95 dogs. Vet Radiol Ultrasound 1999;40:517-522.

44. McEntee MC, Page RC, Novotney CA, et al. Palliative radiotherapy for canine appendicular osteosarcoma. Vet Radiol Ultrasound 1993;34:367-370.

45. Green EM, Adams WM, Forrest LJ. Four fraction palliative radiotherapy for osteosarcoma in 24 dogs. J Am Anim Hosp Assoc 2002;38:445-451.


Click here