On the Forefront: Extended-release liposomal opioids for treating pain in dogs - Veterinary Medicine
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On the Forefront: Extended-release liposomal opioids for treating pain in dogs


VETERINARY MEDICINE


5. Dohoo S. Steady-state pharmacokinetics of oral sustained-release morphine sulphate in dogs. J Vet Pharmacol Ther 1997;20:129-133.

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9. Smith LJ, Krugner-Higby L, Clark M, et al. A single dose of liposome-encapsulated oxymorphone or morphine provides long-term analgesia in an animal model of neuropathic pain. Comp Med 2003;53:280-287.

10. Krugner-Higby L, Smith LJ, Clark M, et al. Liposome-encapsulated oxymorphone hydrochloride provides prolonged relief of postsurgical visceral pain in rats. Comp Med 2003;53:270-279.

11. Clark MD, Krugner-Higby L, Smith LJ, et al. Evaluation of liposome-encapsulated oxymorphone hydrochloride in mice after splenectomy. Comp Med 2004;54:558-563.

12. Smith LJ, Krugner-Higby L, Trepanier LA, et al. Sedative effects and serum drug concentrations of oxymorphone and metabolites after subcutaneous administration of a liposome-encapsulated formulation in dogs. J Vet Pharmacol Ther 2004;27:369-372.

The information for "On the Forefront" was provided by Lesley J. Smith, DVM, DACVA, Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706.


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