A variety of conditions in dogs and cats cause hypercoagulability and may benefit from prophylactic heparin therapy. Prospective,
controlled clinical trials are needed to determine optimal treatment strategies. Although low-molecular-weight heparins are
advantageous for treating hypercoagulability in people, the convenience of once-daily dosing for people appears to be lost
in small animals. It is more expensive to treat with low-molecular-weight heparin compared with unfractionated heparin, and
no evidence exists to support improved outcomes. Clinical research is ongoing to identify situations in which low-molecular-weight
heparins are preferred for anticoagulant therapy in dogs and cats.
Bryan E. Harnett, DVM
5914 Johnson Drive
Mission, KS 66202
Marie E.Kerl, DVM, DACVIM, DACVECC
Department of Veterinary Medicine and Surgery
College of Veterinary Medicine
University of Missouri
379 East Campus Drive
Columbia, MO 65211
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