Is it immune-mediated neutropenia? - Veterinary Medicine
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Is it immune-mediated neutropenia?
Since no test definitively identifies an immune-mediated neutropenia in dogs and cats, diagnosing this condition and treating it appropriately rely on your excluding thecommon causes of neutropenia, such as infections and drug reactions.


6. Brown CD, Parnell NK, Schulman RL, et al. Evaluation of clinicopathological features, response to treatment, and risk factors associated with idiopathic neutropenia in dogs: 11 cases (1990-2002). J Am Vet Med Assoc 2006;229(1):87-91.

7. Dale DC. Immune and idiopathic neutropenia. Curr Opin Hematol 1998;5:33-36.

8. Currie MS, Weinberg JB, Rustagi PK, et al. Antibodies to granulocyte precursors in selective myeloid hypoplasia and other suspected autoimmune neutropenias: use of HL-60 cells as targets. Blood 1987;69:529-536.

9. Starkebaum G, Price T, Lee MY, et al. Autoimmune neutropenia in systemic lupus erythematosus. Arthritis Rheum 1978;21:504-512.

10. Felchle LM, McPhee LA, Kerr ME, et al. Systemic lupus erythematosus and bone marrow necrosis in a dog. Can Vet J 1996;37:742-744.

11. Breedveld FC, Lafeber GJ, Doekes G, et al. Felty syndrome: autoimmune neutropenia or immune-complex-mediated disease? Rheumatol Int 1985;5:253-258.

12. Maheshwari C, Christensen RD, Calhoun DA. Immune-mediated neutropenia in the neonate. Acta Paediatr Suppl 2002;91:98-103.

13. Moore FM, Bender HS. Neutropenia. In: Feldman BF, Zinkl JG, Jain NC, eds. Schalm's veterinary hematology. 5th ed. Oxford, England: Blackwell Publishing, 2000;350-355.

14. Couto C. Immune-mediated neutropenia. In: Feldman BF, Zinkl JG, Jain NC, eds. Schalm's veterinary hematology. 5th ed. Oxford, England: Blackwell Publishing, 2000;815-818.

15. Gould DJ, Murphy K, Rudorf H, et al. Canine monocytic ehrlichiosis presenting as acute blindness 36 months after importation into the UK. J Small Anim Pract 2000;41:263-265.

16. Brown MR, Rogers KS. Neutropenia in dogs and cats: a retrospective study of 261 cases. J Am Anim Hosp Assoc 2001;37:131-139.

17. Swenson CL, Kociba GJ, O'Keefe DA, et al. Cyclic hematopoiesis associated with feline leukemia virus infection in two cats. J Am Vet Med Assoc 1987;191:93-96.

18. Shelton GH, Abkowitz JL, Linenberger ML, et al. Chronic leukopenia associated with feline immunodeficiency virus infection in a cat. J Am Vet Med Assoc 1989;194:253-255.

19. Feldman BF. Neutropenia in small animals. Vet Forum 1999;16:38-45.

20. Farris B. Inhibition of myelopoiesis by serum from dogs exposed to estrogen. Am J Vet Res 1993;54:1374-1379.

21. Shelton GH, Grant CK, Linenberger ML, et al. Severe neutropenia associated with griseofulvin therapy in cats with feline immunodeficiency virus infection. J Vet Intern Med 1990;4:317-319.

22. Peterson ME, Kintzer PP, Hurvitz AI. Methimazole treatment of 262 cats with hyperthyroidism. J Vet Intern Med 1988;2:150-157.

23. Weiss DJ. Bone marrow necrosis in dogs: 34 cases (1996-2004). J Am Vet Med Assoc 2005;227:263-267.


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