A review of selected systemic antifungal drugs for use in dogs and cats - Veterinary Medicine
  • SEARCH:
Medicine Center
DVM Veterinary Medicine Featuring Information from:

ADVERTISEMENT

A review of selected systemic antifungal drugs for use in dogs and cats
This pharmacologist reviews a few of your antifungal choices, specifically the azoles andterbinafine. These drugs have a broad spectrum of activity—with some important differences.


VETERINARY MEDICINE


10. Ward KW, Stelman GJ, Morgan JA, et al. Development of an in vivo preclinical screen model to estimate absorption and first-pass hepatic extraction of xenobiotics. II. Use of ketoconazole to identify P-glycoprotein/CYP3A-limited bioavailability in the monkey. Drug Metab Dispos 2004;32(2):172-177.

11. Mealey KL. Therapeutic implications of the MDR-1 gene. J Vet Pharmacol Ther 2004;27(5):257-264.

12. Myre SA, Schoeder TJ, Grund VR, et al. Critical ketoconazole dosage range for ciclosporin clearance inhibition in the dog. Pharmacology 1991;43(5):233-241.

13. McAnulty JF, Lensmeyer GL. The effects of ketoconazole on the pharmacokinetics of cyclosporine A in cats. Vet Surg 1999;28(6):448-455.

14. Menegola E, Broccia ML, Di Renzo F, et al. Dysmorphogenic effects of some fungicides derived from the imidazole on rat embryos cultured in vitro. Reprod Toxicol 2006;21(1):74-82.

15. Willard MD, Nachreiner RF, Howard VC, et al. Effect of long-term administration of ketoconazole in cats. Am J Vet Res 1986;47(12):2510-2513.

16. Bennet JE. Antimicrobial agents: antifungal agents. In: Brunton LL, Lazo JS, Parker KL, eds. Goodman & Gilman's pharmacological basis of therapeutics. 11th ed. New York: McGraw-Hill, 2005;1225-1241.

17. Berman J. Clinical status of agents being developed for leishmaniasis. Expert Opin Investig Drugs 2005;14(11):1337-1346.

18. Kohler LM, Monteiro PC, Hahn RC, et al. In vitro susceptibilities of isolates of Sporothrix schenckii to itraconazole and terbinafine. J Clin Microbiol 2004;42(9):4319-4320.

19. Chapman SW, Pappas P, Kauffmann C, et al. Comparative evaluation of the efficacy and safety of two doses of terbinafine (500 and 1000 mg day(-1)) in the treatment of cutaneous or lymphocutaneous sporotrichosis. Mycoses 2004;47(1-2):62-68.

20. Van Cauteren H, Heykants J, De Coster R, et al. Itraconazole: pharmacologic studies in animals and humans. Rev Infect Dis 1987;9(suppl 1):S43-S46.

21. Boothe DM, Herring I, Calvin J, et al. Itraconazole disposition after single oral and intravenous and multiple oral dosing in healthy cats. Am J Vet Res 1997;58(8):872-877.

22. Pinchbeck LR, Hillier A, Kowalski JJ, et al. Comparison of pulse administration versus once daily administration of itraconazole for the treatment of Malassezia pachydermatis dermatitis and otitis in dogs. J Am Vet Med Assoc 2002;220(12):1807-1812.

23. Legendre AM, Rohrbach BW, Toal RL, et al. Treatment of blastomycosis with itraconazole in 112 dogs. J Vet Intern Med 1996;10(6):365-371.

24. Queiroz-Telles F, Purim KS, Boguszewski CL, et al. Adrenal response to corticotrophin and testosterone during long-term therapy with itraconazole in patients with chromoblastomycosis. J Antimicrob Chemother 1997;40(6):899-902.

25. Lavrijsen K, van Houdt J, Thijs D, et al. Interaction of miconazole, ketoconazole and itraconazole with rat-liver microsomes. Xenobiotica 1987;17(1):45-57.


ADVERTISEMENT

Source: VETERINARY MEDICINE,
Click here