Toxicology Brief: Brunfelsia species: Beautiful but deadly - Veterinary Medicine
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Toxicology Brief: Brunfelsia species: Beautiful but deadly


VETERINARY MEDICINE


CONCLUSION

Although there are only a few published reports of Brunfelsia species toxicosis in dogs, the information collected by the ASPCA APCC from 2001 to 2006 indicates that the number of cases is on the rise, probably because of the increased popularity and availability of Brunfelsia species in the United States.

Clinical signs of Brunfelsia species toxicosis are usually observed within the first few hours after exposure and mainly consist of CNS and gastrointestinal effects. Some CNS signs may be similar to those caused by strychnine.

Treatment is aimed at decontamination, seizure control, and supportive care. Since Brunfelsia species toxicosis can cause potentially life-threatening effects, all exposures should be taken seriously and treated aggressively.

"Toxicology Brief" was contributed by Safdar A. Khan, DVM, MS, PhD, DABVT, ASPCA Animal Poison Control Center, 1717 S. Philo Road, Suite 36, Urbana, IL 61802. The department editor is Petra Volmer, DVM, MS, DABVT, DABT.

REFERENCES

1. Burrows GE, Tyrl RJ. Brunfelsia L. In: Toxic plants of North America. Ames: Iowa State University Press, 2001;1107-1108.

2. Spainhour CB Jr, Fiske RA, Flory W, et al. A toxicological investigation of the garden shrub Brunfelsia calcyina var. floribunda (yesterday-today-and-tomorrow) in three species. J Vet Diagn Investi 1990;2(1):3-8.

3. Mason J, Khan SA, Gwaltney-Brant S. Toxicant exposures in small animals: recently recognized animal toxicants. In: Kirk RW, Bonagura JD, eds. Current veterinary therapy small animal practice (in press).

4. AnTox Database. Urbana, Ill: ASPCA Animal Poison Control Center, 2001-2006.

5. McBarron EJ, de Sarem W. Letter: Poisoning of dogs by the fruits of the garden shrub Brunfelsia bonodora. Aust Vet J 1975;51(5):280.

6. Neilson J, Burren V. Intoxication of two dogs by fruit of Brunfelsia australis. Aust Vet J 1983;60(12):378-380.

7. Banton MI, Jowett PL, Renegar KR, et al. Brunfelsia pauciflora ("yesterday, today and tomorrow") poisoning in a dog. Vet Hum Toxicol 1989;31(5):496-497.


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