Although there are only a few published reports of Brunfelsia species toxicosis in dogs, the information collected by the ASPCA APCC from 2001 to 2006 indicates that the number of cases
is on the rise, probably because of the increased popularity and availability of Brunfelsia species in the United States.
Clinical signs of Brunfelsia species toxicosis are usually observed within the first few hours after exposure and mainly consist of CNS and gastrointestinal
effects. Some CNS signs may be similar to those caused by strychnine.
Treatment is aimed at decontamination, seizure control, and supportive care. Since Brunfelsia species toxicosis can cause potentially life-threatening effects, all exposures should be taken seriously and treated aggressively.
"Toxicology Brief" was contributed by Safdar A. Khan, DVM, MS, PhD, DABVT, ASPCA Animal Poison Control Center, 1717 S. Philo
Road, Suite 36, Urbana, IL 61802. The department editor is Petra Volmer, DVM, MS, DABVT, DABT.
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