Canine and feline histoplasmosis: A review of a widespread fungus - Veterinary Medicine
Medicine Center
DVM Veterinary Medicine Featuring Information from:


Canine and feline histoplasmosis: A review of a widespread fungus
Infection with this pathogenic fungus most commonly results from inhaling spores from contaminated soil. The infection should be treated promptly to avoid dissemination, which carries a poorer prognosis.


71. LeMonte AM, Washum KE, Smedema ML, et al. Amphotericin B combined with itraconazole or fluconazole for treatment of histoplasmosis. J Infect Dis 2000;182(2):545-550.

72. Hector RF. An overview of antifungal drugs and their use for treatment of deep and superficial mycoses in animals. Clin Tech Small Anim Pract 2005;20(4):240-249.

73. Nomeir AA, Kumari P, Hilbert MJ, et al. Pharmacokinetics of SCH 56592, a new azole broad-spectrum antifungal agent, in mice, rats, rabbits, dogs, and cynomolgus monkeys. Antimicrob Agents Chemother 2000;44(3):727-731.

74. Roffey SJ, Cole S, Comby P, et al. The disposition of voriconazole in mouse, rat, rabbit, guinea pig, dog, and human. Drug Metab Dispos 2003;31(6):731-741.

75. Malik R, Craig AJ, Wigney DI, et al. Combination chemotherapy of canine and feline cryptococcosis using subcutaneously administered amphotericin B. Aust Vet J 1996;73(4):124-128.

76. Bekersky I, Boswell GW, Hiles R, et al. Safety and toxicokinetics of intravenous liposomal amphotericin B (AmBisome) in beagle dogs. Pharm Res 1999;16(11):1694-1701.

77. Dupont B. Overview of the lipid formulations of amphotericin B. J Antimicrob Chemother 2002;49(suppl):31-36.

78. Kleinberg M. What is the current and future status of conventional amphotericin B? Int J Antimicrob Agents 2006;27(suppl 1):12-16.

79. Legendre AM, Rohrbach BW, Toal RL, et al. Treatment of blastomycosis with itraconazole in 112 dogs. J Vet Intern Med 1996;10(6):365-371.

80. Berthelin CF, Legendre AM, Bailey CS. Cryptococcosis of the nervous system in dogs: Part 2. Diagnosis, treatment, monitoring, and prognosis. Prog Vet Neurol 1994;5:136-145.

81. Legendre AM. Antimycotic drug therapy. In: Bonagura JD, ed. Kirk's current veterinary therapy XII small animal practice. Philadelphia, Pa: WB Saunders Co, 1995;329-331.

82. Davies SF, Colbert RL. Concurrent human and canine histoplasmosis from cutting decayed wood. Ann Intern Med 1990;113(3):252-253.

83. Brunker JD, Hoover JP. B-cell lymphoma in a dog with ehrlichiosis (Ehrlichia canis) and systemic histoplasmosis (Histoplasma capsulatum). Can Vet J 2007;48(3):292-295.

84. Krawiec DR, McKiernan BC, Twardock R, et al. Use of an amphotericin B lipid complex for treatment of blastomycosis in dogs. J Am Vet Med Assoc 1996;209(12):2073-2075.

85. Deepe GS Jr. Histoplasma capsulatum. In: Mandell GLB, Bennett JE, Dolin R, eds. Principles and practice of infectious diseases. 5th ed. New York: Churchill Livingstone, 2000;2718-2733.

86. Gustafson TL, Kaufman L, Weeks R, et al. Outbreak of acute pulmonary histoplasmosis in members of a wagon train. Am J Med 1981;71(5):759-765.


Click here