A fresh look at identifying sepsis in cats - Veterinary Medicine
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A fresh look at identifying sepsis in cats
New criteria have made the diagnosis of sepsis more specific. However, most of the studies have evaluated people. Find out how these new criteria relate to cats—and how to treat septic cats once you've identified them.



1. Levy MM, Fink MP, Marshall JC, et al. 2001 SCCM/ESICM/ACCP/ATS/SIS international sepsis definitions conference. Intensive Care Med 2003;29(4):530-538.

2. American college of chest physicians/society of critical care medicine consensus conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992;20(6):864-874.

3. Hauptman JG, Walshaw R, Olivier NB. Evaluation of the sensitivity and specificity of diagnostic criteria for sepsis in dogs. Vet Surg 1997;26(5):393-397.

4. Waddell LS, Brady CA, Drobatz KJ. Risk factors, prognostic indicators, and outcome of pyothorax in cats: 80 cases (1986-1999). J Am Vet Med Assoc 2002;221(6):819-824.

5. Costello MF, Drobatz KJ, Aronson LR, et al. Underlying cause, pathophysiologic abnormalities, and response to treatment in cats with septic peritonitis: 51 cases (1990-2001). J Am Vet Med Assoc 2004;225(6):897-902.

6. Sergeeff JS, Armstrong PJ, Bunch SE. Hepatic abscesses in cats: 14 cases (1985-2002). J Vet Intern Med 2004;18(3):295-300.

7. Bernard GR, Vincent JL, Laterre PF, et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 2001;344(10):699-709.

8. Brady CA, Otto CM, Van Winkle TJ, et al. Severe sepsis in cats: 29 cases (1986-1998). J Am Vet Med Assoc 2000;217(4):531-535.

9. de Laforcade AM, Rozanski EA, Freeman LM, et al. Serial evaluation of protein C and antithrombin in dogs with sepsis. J Vet Intern Med 2008;22(1):26-30.

10. King LG. Postoperative complications and prognostic indicators in dogs and cats with septic peritonitis: 23 cases (1989-1992). J Am Vet Med Assoc 1994;204(3):407-414.

11. Bentley AM, Otto CM, Shofer FS. Comparison of dogs with septic peritonitis: 1988-1993 versus 1999-2003. J Vet Emerg Crit Care 2007;17(4):391-398.

12. Barrs VR, Allan GS, Martin P, et al. Feline pyothorax: a retrospective study of 27 cases in Australia. J Feline Med Surg 2005;7(4):211-222.

13. Malik R, Barrs VR, Church DB, et al. Vegetative endocarditis in six cats. J Feline Med Surg 1999;1(3):171-180.

14. Parsons KJ, Owen LJ, Lee K, et al. A retrospective study of surgically treated cases of septic peritonitis in the cat (2000-2007). J Small Anim Pract 2009;50(10):518-524.

15. de Laforcade AM, Freeman LM, Shaw SP, et al. Hemostatic changes in dogs with naturally occurring sepsis. J Vet Intern Med 2003;17(5):674-679.

16. Gebhardt C, Hirschberger J, Rau S, et al. Use of C-reactive protein to predict outcome in dogs with systemic inflammatory response syndrome or sepsis. J Vet Emerg Crit Care 2009;19(5):450-458.

17. Otto CM, Drobatz K, Soter C. Endotoxemia and tumor necrosis factor activity in dogs with naturally occurring parvoviral enteritis. J Vet Intern Med 1997;11(2):65-70.

18. DeClue AE, Williams KJ, Sharp C, et al. Systemic response to low-dose endotoxin infusion in cats. Vet Immunol Immunopathol 2009;132(2-4):167-174.

19. Moldawer LL, Marano MA, Wei H, et al. Cachectin/tumor necrosis factor-alpha alters red blood cell kinetics and induces anemia in vivo. FASEB J 1989;3(5):1637-1643.


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