One week later, the left eye had increased periocular tear staining, mild blepharospasm, mildly injected conjunctiva, and
a 2-mm-x-4-mm area of positive fluorescein uptake in the dorsal portion of the cornea. The results of the remainder of the
ophthalmic examination were normal. The corneal ulcer appeared to be decreasing in size and there was no lip of loose epithelium,
so the antibiotic ophthalmic ointment was continued and the topical morphine was discontinued.
At a three-week recheck appointment, the left eye still had moderate blepharospasm and mildly injected conjunctiva. The dorsal
cornea had a 4-mm-x-1-mm area of positive fluorescein uptake, and a lip of loose epithelium was present around the ulcerated
area. The loose epithelium indicated that the ulcer had not healed and, in fact, had again become undermined.
We again applied a topical anesthetic and débrided the ulcer with a sterile cotton-tipped applicator soaked in dilute povidone-iodine
solution. This time the 3.5-mm, diamond-tipped motorized burr was applied to the surface of the corneal ulcer to provide additional
epithelial débridement and to remove a thin area of the underlying corneal stroma, which would improve the likelihood of good
epithelial adherence (Figure 5).4
5. The dog in this report undergoing corneal débridement with a diamond burr to treat a spontaneous chronic corneal epithelial
defect in the left eye.
The dog's therapy of topical 1% morphine solution administered three times a day for pain management was reinstituted and
the antibiotic ophthalmic ointment was continued. The owner declined placement of a bandage contact lens to protect the cornea
and help alleviate pain.
A two-week recheck appointment was scheduled, but the owner instead returned in three weeks.
At the recheck appointment, the dog showed no clinical signs of ocular discomfort. No areas of fluorescein dye uptake were
present on either cornea. A small area of granulation tissue was present at the site of the ulcer in the left eye. Medications
were discontinued, and no rechecks were scheduled. The client was informed of the potential for the SCCED to recur in either
the same or the contralateral eye.
The dog had no further ocular lesions. However, it was euthanized eight months later because of an unrelated disease.
Corneal ulcers are one of the most common ophthalmic diseases seen in veterinary private practice. The affected patient may
present with a history of suspected trauma to the eye or without any apparent cause. The results of a comprehensive ophthalmic
examination as well as the dog's signalment and history are important factors to take into consideration when determining
the underlying cause and instituting appropriate therapy. A routine, uncomplicated corneal ulcer generally heals quickly,
and thus, an ulcer that does not heal quickly should be further evaluated to determine the underlying cause.
SCCED has also been called indolent ulcer, refractory ulcer, boxer ulcer, persistent corneal erosion, recurrent ulcer, and nonhealing erosion.1,2,6 SCCED is a unique form of superficial corneal ulceration that fails to heal through a normal wound healing process.6,9 This delayed healing time usually lasts more than 14 days.