Articles by Butch KuKanich, DVM, PhD, DACVCP - Veterinary Medicine
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Articles by Butch KuKanich, DVM, PhD, DACVCP

NSAIDs, anesthesia, and the kidneys: What they are not telling you (Proceedings)

Aug 1, 2010

Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most widely used analgesic drug class in human and veterinary medicine. NSAIDs are effective due to both peripheral and central mechanisms of analgesia.

The all-natural drugs you may already be using (Proceedings)

Aug 1, 2010

Many clients are requesting all natural and alternative treatment options as they are under the impression that they produce less adverse effects than pharmaceutical compounds. This is a common misconception as some of the most toxic compounds known are natural products such as botulinum toxin, ricin, cobra venom, and uranium, among many others.

Antiemetic therapy (Proceedings)

Aug 1, 2010

The vomiting reflex is a complex mechanism that can be initiated peripherally from the GI tract, pharynx, chemoreceptor trigger zone (CRTZ), and vestibular systems or centrally at the emetic center in the brain. Direct stimulation of the pharynx can result in vomiting, although this is a relatively infrequent cause in animals.

"New" antimicrobials in veterinary medicine (Proceedings)

Aug 1, 2010

Unasyn 1.5 g vial (Generic ~$4.50) is commercially available containing ampicillin 1 g and sulbactam 0.5 g. Sulbactam is a beta lactamase inhibitor, therefore many people think of this drug as "injectable Clavamox."

Top clinical pharmacology myths busted (Proceedings)

Aug 1, 2010

Morphine cannot be used in cats due to CNS excitement and slow metabolism and morphine causes histamine release in dogs resulting in severe hypotension and the most common adverse effects of opioids are cardiovascular and respiratory depression.

Opioids use with inpatients (Proceedings)

Aug 1, 2010

Opioids are commonly used in veterinary medicine for their analgesic, sedative, and anti-diarrheal properties. Opioids are also effective antitussive agents and in appropriate doses opioids can provide anxiolytic effects.

Glucocorticoids and shock, what are we doing now? (Proceedings)

Aug 1, 2010

Shock can be classified into general categories: hypovolemic, maldistribution, and cardiogenic. Hypovolemic shock is due to a diminished volume of fluids and can occur in severe dehydration (Parvoviral gastroenteritis, hemorrhagic gastroenteritis) or hemorrhage.

Bacterial culture and sensitivities, what do they really mean? (Proceedings)

Aug 1, 2010

Treatment of bacterial infections can be difficult and frustrating. There are many different opinions for empiric antimicrobial therapy.

Opioid and tramadol use in outpatients: What are reasonable choices? (Proceedings)

Aug 1, 2010

Nonsteroidal antiinflamatory drugs (NSAIDs) are commonly used in veterinary medicine for a variety of reasons including the management of acute postoperative pain and chronic pain associated with degenerative joint disease among other conditions. However adverse effects preclude their use in many patients and severe adverse effects such as nephrotoxicity, hepatotoxicity, and gastrointestinal ulceration and perforation, and death occur infrequently.

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