Articles by Barrak Pressler, DVM, PhD, DACVIM - Veterinary Medicine
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Articles by Barrak Pressler, DVM, PhD, DACVIM

Barrak Pressler, DVM, PhD, DACVIM

Non-core vaccines: FIP, canine corona, lyme, and Bordetella (Proceedings)
November 1, 2010

Non-core vaccines are those which we as a profession have determined are not recommended for all dogs or cats. Vaccination, in general, has the benefit of potentially lessening the prevalence or severity of disease, ensuring that patients are examined on a regular basis, increasing practice revenue, and potentially saving clients money in the long-run.

Using titers to diagnose disease: when is a positive a positive? (Proceedings)
November 1, 2010

For most diagnostic tests, the 'titer' is the minimum dilution of a substance that is required to yield a positive result. For example, for detection of anti-Leptospira sp. Antibodies, the titer is the dilution of serum which still causes microbes to crosslink.

Evidence-based management of ITP (Proceedings)
November 1, 2010

Dogs with immune-mediated thrombocytopenia (ITP) usually present with platelet counts low enough to be considered life-threatening, although overt signs of bleeding are uncommon. Owners usually only note anorexia or lethargy, although in some cases epistaxis, cutaneous bruising/petecchi?/echymoses, or oral bleeding may be noted.

Polyarthritis: clinical approach to medical joint disease (Proceedings)
November 1, 2010

Nontraumatic inflammatory joint disease is a relatively common, but under-recognized, cause of fever and morbidity in dogs. In one review of 66 dogs referred for fever of unknown origin to a veterinary teaching hospital, approximately 8% were diagnosed with immune-mediated polyarthritis.

Hot dogs: fever of unknown origin (Proceedings)
November 1, 2010

In human medicine, fever of unknown origin (FUO) is defined as pyrexia of greater than two to three weeks duration (i.e. sufficient time for self-limiting infections to resolve) during which repeat physical examinations and standard diagnostic testing have failed to reveal an underlying cause.

Immunosuppressive drugs: beyond glucocorticoids (Proceedings)
November 1, 2010

Glucocorticoids are the most commonly used drugs for immunosuppression of dogs and cats with immune-mediated diseases because they induce rapid, non-specific inhibition of the immune system by reducing inflammation-associated gene transcription, inhibiting intracellular signaling pathways, down-regulating cell membrane expression of adhesion proteins, and slowing cell proliferation.

Evidence-based management of IMHA (Proceedings)
November 1, 2010

Immune-mediated hemolytic anemia is one of the most common reasons for referral to veterinary internists. The most common presenting complaint is that the patient is inadequately responding to appropriate imunosuppression.

Immunosuppressive drugs: Beyond glucocorticoids (Proceedings)
April 1, 2010

There is no question that glucocorticoids (GCs) remain the mainstay of immunosuppressive therapy in small animal medicine. However other drugs are available that can be used in conjunction with GCs in order to provide synergistic immunosuppression and thus allow lower GC dosage, more specifically target certain arms of the immune system, and provide proven superior immunosuppression to GCs in a few diseases.

Update on nephrotic syndrome (Proceedings)
April 1, 2010

Nephrotic syndrome is an uncommon to rare complication of protein-losing nephropathies. Diagnosis of nephrotic syndrome requires the concurrent presence of proteinuria, hypoalbuminemia, third-space accumulation of fluid, (such as ascites) and hyperlipidemia; when present, this diagnosis is pathognomonic for glomerular disease.


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