Sheep virus finding reshapes human cancer data

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New York-Researchers studying human lung cancer have recently learned how a sheep cancer virus attaches to cells, and believe this knowledge could lead to a new way to deliver gene therapy to human lungs.

New York-Researchers studying human lung cancer have recently learned how a sheepcancer virus attaches to cells, and believe this knowledge could lead toa new way to deliver gene therapy to human lungs.

The virus, Jaagsiekte sheep retrovirus (JSRV), causes a contagious formof lung cancer in sheep which resembles human bronchiolo-alveolar carcinoma,according to Dr. Hung Fan from the University of California, Irvine. Thecancer, not linked to smoking, accounts for 25 percent of all lung cancercases in the United States.

Findings from the study were published in the April 10 proceedings ofthe National Academy of Sciences.

Researchers now plan to use the data to breed mice that have human HYAL2as models for the study of how JSRV causes cancer.

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